Patient-reported outcomes (PROs) is an umbrella term covering a range of subjective reports patients make regarding health, disease, or treatment, generally via structured validated questionnaires. In addition to outcomes such as distress, PROs include functional status, well-being, symptoms, health-related quality of life, and so on. PROs can be used in a number of ways to promote the patient-centeredness and improve the quality of care. In this session, a panel will highlight a number of tools developed to facilitate the use of PROs in clinical practice. These tools include the Patient-Reported Outcomes Measurement Information System (PROMIS), a User's Guide for implementing PROs in clinical practice, standards for reporting the results of randomized clinical trials that included PRO endpoints, and a Reader's Guide to the PRO literature directed at clinicians who may be unfamiliar with PROs. This session will provide an overview of the tools and then demonstrate examples of their application in practice.